KIU Publications

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2026 Faculty of Biomedical Sciences F1000Research

Cross-Border Ebola Virus Disease Preparedness in Uganda and the Democratic Republic of the Congo: A Systematic Review of Health Security Capacities, Gaps, and Priorities

Chinyere Nkemjika Anyanwu; Rachelle Soki Marasi; Regina Idu Ejemot-Nwadiaro; Bunu Umi Omar; Theoneste Hakizimana; Nwanganga Ihuoma Ubosi; Zeinab Adam Abakar Mohamed; Chima Paul Okechukwu Ugwu; Emeka Anyanwu

Background Recurrent Ebola virus disease (EVD) outbreaks in the Democratic Republic of the Congo (DRC) continue to pose substantial cross-border health security risks to neighbouring countries, particularly Uganda. Although numerous preparedness initiatives have been implemented to prevent, detect, and respond to cross-border Ebola transmission, evidence on their effectiveness, strengths, and persistent gaps remains fragmented across peer-reviewed and grey-literature sources. This review synthesized available evidence on cross-border Ebola preparedness in Uganda and the DRC and identified key capacities, challenges, and priorities for strengthening regional healthBackground Recurrent Ebola virus disease (EVD) outbreaks in the Democratic Republic of the Congo (DRC) continue to pose substantial cross-border health security risks to neighbouring countries, particularly Uganda. Although numerous preparedness initiatives have been implemented to prevent, detect, and respond to cross-border Ebola transmission, evidence on their effectiveness, strengths, and persistent gaps remains fragmented across peer-reviewed and grey-literature sources. This review synthesized available evidence on cross-border Ebola preparedness in Uganda and the DRC and identified key capacities, challenges, and priorities for strengthening regional health