KIU Publications

Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.

Scholarly Work

KIU publications archive

Search peer-reviewed articles, reports, books, policy briefs and other scholarly outputs by KIU researchers and collaborators.

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2026 School of Pharmacy

RTS,S/AS01 mRNA Booster Platforms for Sustaining Protective Immunity Against Plasmodium Falciparum in African Children

Mangen Joshua Fred

2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 120-125

Malaria caused by Plasmodium falciparum remained a leading cause of morbidity and mortality among African children, with hundreds of thousands of paediatric deaths annually despite expanded control measures. The RTS,S/AS01 pre-erythrocytic vaccine had demonst...

2026 School of Pharmacy

RNA Interference Therapeutics Targeting Hepatic Gluconeogenesis Pathways in Type 2 Diabetes Management

Nakawungu Catherine

2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 115-119

Type 2 diabetes mellitus was characterized by chronic hyperglycemia resulting from insulin resistance and impaired regulation of hepatic glucose production. Excessive hepatic gluconeogenesis was a major contributor to fasting hyperglycemia and remained incomp...

2026 School of Pharmacy

Reprogramming Metabolic Dysfunction using Nanotechnology: Implications for Obesity and Type 2 Diabetes

Nakawungu Catherine

2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 110-114

Obesity and type 2 diabetes (T2D) represent a major global health burden, with increasing prevalence linked to sedentary lifestyles, poor dietary habits, and genetic predisposition. These conditions are strongly interconnected through a range of metabolic dys...

2026 Faculty of Biomedical Sciences

Prevalence of Anemia in Sickle Cell Patients in Ugandan Hospitals: A Narrative Review

Atukunda Derrick

2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 105-109

Sickle cell disease (SCD), particularly sickle cell anemia (HbSS), is intrinsically a chronic hemolytic anemia, but the severity and hospital burden of anemia vary widely across patients and care settings. In Uganda, where SCD is common and malaria and undern...

2026 School of Pharmacy

Precision SGLT2 Inhibitor Strategies for Cardiovascular and Renal Outcomes in Type 2 Diabetes

Waiswa Arajab

2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 100-104

Cardiovascular and renal complications remained the leading causes of morbidity and mortality in type 2 diabetes, affecting approximately 537 million adults globally in 2021 with projections exceeding 783 million by 2045. Sodium-glucose cotransporter-2 (SGLT2...

2026 Faculty of Biomedical Sciences

Precision Nanomedicine for Obesity and Diabetes Management: From Pathophysiology to Targeted Therapy

Atukunda Derrick

2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 94-99

Obesity and type 2 diabetes (T2D) are major contributors to the global burden of chronic diseases, with their coexistence exacerbating the health challenges faced by millions of people worldwide. The close association between obesity and insulin resistance in...

2026 School of Pharmacy

Polymeric Nanoparticle Drug Delivery Systems Enhancing Lumefantrine Bioavailability in Uncomplicated Malaria Treatment

Waiswa Arajab

2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 89-93

Malaria remained a major global health challenge, with uncomplicated malaria accounting for most clinical cases in endemic regions. Artemisinin-based combination therapy remained the cornerstone of treatment, and lumefantrine played a crucial role as the long...

2026 School of Pharmacy

Plant-Derived Bioactives in Nanoplatforms for Obesity and Cardiometabolic Risk Reduction

Namirimu Sandrah

2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 83-88

Plant-derived bioactives offer pleiotropic actions relevant to obesity and cardiometabolic risk, including modulation of appetite and gut hormone signaling, suppression of adipose inflammation, improvement of insulin sensitivity, regulation of lipid metabolis...

2026 School of Pharmacy

Plant-Derived Bioactives in Nano-Platforms for Diabetes and Metabolic Syndrome Therapy

Kabazzi Douglas T.

2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 77-82

Diabetes and metabolic syndrome (MetS) are interconnected metabolic disorders characterized by hyperglycemia, insulin resistance, central obesity, dyslipidemia, hypertension, oxidative stress, and chronic inflammation. Plant-derived bioactives including polyp...

2026 School of Pharmacy

Phytochemical Nanoformulations Targeting Adipogenesis, Lipolysis, and Thermogenesis

Omagor Jacob

2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 67-76

Phytochemicals with anti-obesity potential modulate adipogenesis, lipolysis, and thermogenesis through pleiotropic effects on transcriptional networks, mitochondrial function, and inflammatory signaling. However, their clinical impact is frequently limited by...