KIU Publications

Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.

Scholarly Work

KIU publications archive

Search peer-reviewed articles, reports, books, policy briefs and other scholarly outputs by KIU researchers and collaborators.

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2026 School of Natural and Applied Sciences

Smart Nanomaterials for Glucose-Responsive Drug Delivery Systems in Diabetic Patients with Obesity

Maina Mwaura F.

2026 | Research Output Journal of Engineering and Scientific Research | Pp. 68-74

Glucose-responsive drug delivery systems aim to emulate pancreatic feedback by sensing hyperglycemia and releasing therapeutics proportionally, thereby improving time in range while mitigating hypoglycemia. In people with diabetes and coexisting obesity, the...

2026 School of Natural and Applied Sciences

Smart Nanocarriers for Targeted Delivery of Anti Obesity Agents: Precision Medicine Approaches to Metabolic Regulation

Kamanzi Ntakirutimana G.

2026 | Research Output Journal of Engineering and Scientific Research | Pp. 59-67

Obesity is a multifactorial, relapsing disease driven by complex interactions between genetics, environment, and behavior. Conventional systemic pharmacotherapy often fails to provide durable weight loss and is limited by off-target toxicity in the cardiovasc...

2026 School of Natural and Applied Sciences

Smart Nanocarriers for Co-Delivery of Anti-Obesity and Anticancer Agents

Kamanzi Ntakirutimana G.

2026 | Research Output Journal of Engineering and Scientific Research | Pp. 53-58

Obesity and cancer intersect through shared inflammatory, endocrine, and metabolic circuits that amplify risk, accelerate progression, and blunt therapeutic response. Treating them as separate diseases leaves substantial biology unaddressed at the adipose–tum...

2026 School of Natural and Applied Sciences

Smart Insulin Patch Systems for Glucose-Responsive Delivery in Pediatric Type 1 Diabetes

Kibibi Wairimu H.

2026 | Research Output Journal of Engineering and Scientific Research | Pp. 43-52

Type 1 diabetes (T1D) in pediatric populations presented unique therapeutic challenges, with suboptimal glycemic control contributing to acute complications and long-term microvascular disease despite advances in insulin delivery technologies. Smart insulin p...

2026 School of Natural and Applied Sciences

Smart Insulin Patch Delivery Systems for Glucose Responsive Glycemic Control in Diabetic Patients

Kibibi Wairimu H.

2026 | Research Output Journal of Engineering and Scientific Research | Pp. 36-42

Diabetes mellitus affects over 537 million adults globally, with inadequate glycemic control contributing to severe microvascular and macrovascular complications. Conventional insulin therapy, including multiple daily injections and continuous subcutaneous in...

2026 School of Allied Health Sciences

SGLT2 Inhibitors vs Metformin: Cardiovascular Protection in Type 2 Diabetes Patients

Irakoze Mukamana S.

2026 | Research Output Journal of Public Health and Medicine | Pp. 100-106

Type 2 diabetes mellitus affects over 537 million adults globally and represents the leading cause of cardiovascular morbidity and mortality, with diabetic patients experiencing a 2- to 4-fold increased risk of major adverse cardiovascular events compared to...

2026 School of Natural and Applied Sciences

SGLT2 Inhibitors for Diabetic Kidney Disease Prevention: Mechanisms, Clinical Evidence, and Guidelines

Nambi Namusisi H.

2026 | Research Output Journal of Engineering and Scientific Research | Pp. 29-35

Diabetic kidney disease remained a leading cause of end stage renal disease globally, affecting approximately 40% of individuals with diabetes mellitus. Sodium glucose cotransporter 2 inhibitors represented a novel therapeutic class originally developed for g...

2026 Faculty of Science and Technology

RTS, S/AS01 Malaria Vaccine Implementation in High Transmission Sub-Saharan African Pediatric Populations: Efficacy and Challenges

Kato Jumba K.

2026 | Research Output Journal of Engineering and Scientific Research | Pp. 21-28

Malaria remains a leading cause of pediatric morbidity and mortality in sub-Saharan Africa, with Plasmodium falciparum accounting for over 90% of cases in high-transmission regions. The RTS, S/AS01 vaccine represents the first licensed malaria vaccine, target...

2026 Faculty of Clinical Medicine and Dentistry

RTS, S/AS01 Malaria Vaccine Implementation: Efficacy, Safety, and Population-Level Impact in Endemic Regions

Otieno Karanja J.

2026 | Research Output Journal of Public Health and Medicine | Pp. 87-91

Malaria remains the leading cause of morbidity and mortality in sub-Saharan Africa, prompting the development and deployment of vaccination strategies. RTS, S/AS01 was the first malaria vaccine recommended by WHO for children in endemic regions, targeting Pla...

2026 School of Allied Health Sciences

RTS, S/AS01 Malaria Vaccine: Efficacy, Implementation Challenges, and Public Health Impact

Irakoze Mukamana S.

2026 | Research Output Journal of Public Health and Medicine | Pp. 92-99

Malaria remained a major global health burden, with Plasmodium falciparum causing significant morbidity and mortality, particularly among children in sub-Saharan Africa. The RTS, S/AS01 vaccine represents the first licensed malaria vaccine, targeting the circ...