Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.
Scholarly Work
Search peer-reviewed articles, reports, books, policy briefs and other scholarly outputs by KIU researchers and collaborators.
2026 | IAA Journal of Scientific Research | Pp. 124-128
HIV/AIDS remains a significant public health challenge in Sub-Saharan Africa, with Uganda and Nigeria facing high HIV burdens despite efforts to improve care. This review evaluates and compares hospital readiness for HIV/AIDS care in both countries, focusing...
2026 | IAA Journal of Scientific Research | Pp. 119-123
Polygenic risk scores (PRS) are increasingly promoted as tools for improving disease risk stratification and preventive care in primary healthcare settings. By aggregating the effects of thousands of common genetic variants, PRS offer probabilistic insights i...
2026 | IAA Journal of Scientific Research | Pp. 111-118
Obesity-driven type 2 diabetes (T2D) reflects chronic environmental stress overnutrition, inactivity, and circadian disruption imprinted onto chromatin in metabolic tissues. Epigenetic changes integrate nutrient, hormonal, and inflammatory cues into durable p...
2026 | IAA Journal of Scientific Research | Pp. 102-110
Obesity-induced insulin resistance emerges from intertwined host–microbe interactions that reshape intestinal permeability, immune tone, and metabolic signaling. Dysbiosis, characterized by reduced microbial diversity, altered short-chain fatty acid productio...
2026 | IAA Journal of Scientific Research | Pp. 92-101
Diabetic obesity, the coexistence of obesity with type 2 diabetes mellitus (T2DM), represents a syndemic condition characterized by chronic hyperglycemia, insulin resistance, low-grade inflammation, and profound pharmacokinetic variability. Conventional antid...
2026 | IAA Journal of Scientific Research | Pp. 83-91
Severe Plasmodium falciparum malaria constituted a life-threatening parasitic infection characterized by widespread endothelial activation, microvascular sequestration, and systemic inflammation. Type 1 diabetes mellitus is associated with baseline endothelia...
2026 | IAA Journal of Scientific Research | Pp. 78-82
Oxidative stress is a central, converging mechanism underlying neurotoxicity in a broad range of systemic disorders, including diabetes mellitus, malaria, and hepatic dysfunction. In these conditions, excessive reactive oxygen and nitrogen species (ROS/RNS),...
2026 | IAA Journal of Scientific Research | Pp. 71-77
Malaria during pregnancy constituted a major public health challenge in endemic regions, causing maternal anemia, placental infection, low birth weight, and increased perinatal mortality. Pregnant women exhibit increased susceptibility due to immunological ch...
2026 | IAA Journal of Scientific Research | Pp. 65-70
Type 2 diabetes mellitus (T2DM) was characterized by hyperglycemia and frequently accompanied by obesity and elevated cardiovascular risk. Incretin hormone-based therapies, especially glucagon-like peptide-1 receptor agonists (GLP-1 RAs), had demonstrated eff...
2026 | IAA Journal of Scientific Research | Pp. 55-64
Type 2 diabetes mellitus represented a global metabolic crisis characterized by progressive beta cell dysfunction, insulin resistance, and chronic hyperglycemia. Traditional incretin-based therapies targeting glucagon-like peptide 1 (GLP-1) receptors have dem...