Title: Lycopene improves on basic hematological and immunological parameters in diabetes mellitus
Author(s): Ejike Daniel Eze, Adam Moyosore Afodun, Josephine Kasolo and Keneth Iceland Kasozi
Year 2019
Publisher: BMC Research Notes
File: PDF
Keywords: Antioxidants Diabetes Anemia Carotenoids Blood

Objective: Diabetes is associated with an upset of hematological and immunological parameters in humans, however information on the effects of Lycopene is scarce. The aim of the study was to gain information on basic changes in hematological parameters as markers for safety since anemia as a complication in diabetic chemotherapy has been reported. Results: Lycopene had anti-anemic effects and improved on the immune status of diabetic rats and these observations were dose independent. There was a decrease in neutrophil, low neutrophil–lymphocyte ratio and platelet counts and stable albumin, globulin levels. Lycopene could exert its protective effects through a balance of basic hematological physiological variables.