This study explores the ability of Aloe vera, a traditional medicinal plant, to inhibit the
digestive enzyme pancreatic lipase and its potential impact on post-prandial lipidaemia in
adult male Wistar rats. Aloe vera extract was administered in varying doses alongside olive
oil as a source of triglycerides. The study investigates the kinetics of post-prandial blood
triglyceride concentration, Area Under the Curve (AUC) values, and the percentage inhibition
of pancreatic lipase. The results reveal significant inhibition of pancreatic lipase, indicating
a potential role in moderating post-prandial blood lipid levels. The inhibition type is suggested to be a mixed type, combining uncompetitive and competitive characteristics. This
finding suggests that Aloe vera may have therapeutic potential in managing conditions
related to post-prandial dyslipidaemia, such as diabetes.