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Title: | Studies on Fertility Hormone in Azoospermia Men Attending Imo State Specialist Hospital, Owerri |
Author(s): | Ukamaka Edward1, Marvis U. Okehie1, Emmanuel Chinedu Onuoha2 and *Emmanuel Ifeanyi Obeagu3 |
Year | 2023 |
Publisher: | NEWPORT INTERNATIONAL JOURNAL OF RESEARCH IN MEDICAL SCIENCES |
URI: | https://publications.kiu.ac.ug/publication-page.php?i=studies-on-fertility-hormone-in-azoospermia-men-attending-imo-state-specialist-hospital-owerri |
File: | ![]() |
Keywords: | fertility hormone azoospermia men |
Azoospermia, a condition characterized by the absence of sperm in a man's semen, affects approximately 1% of the
male population and accounts for about 10 to 15% of male infertility cases. This study aimed to assess the fertility
hormone levels in Azoospermia patients in Owerri. A cross-sectional study included twenty-five Azoospermia
patients attending the fertility clinic at Imo Specialist Hospital and twenty-five healthy individuals as a control
group. Venous blood samples were collected and analyzed for serum testosterone, follicle-stimulating hormone
(FSH), and luteinizing hormone (LH) using the ELISA method. The results indicated that infertile subjects had
significantly higher levels of FSH (9.91 ± 3.69 IU/L) compared to control subjects (5.54 ± 0.90 IU/L) (P = 0.0001).
Similarly, infertile subjects showed significantly higher levels of LH (8.50 ± 2.63 IU/L) compared to control subjects
(4.75 ± 1.15 IU/L) (P = 0.0001). In contrast, the testosterone levels in infertile subjects (2.56 ± 0.97 IU/L) were
significantly lower than those in control subjects (4.80 ± 1.19 IU/L) (P = 0.0001). In conclusion, the findings of this
study demonstrate a significant increase in gonadotropins (FSH and LH) and a significant decrease in testosterone
levels in males with Azoospermia.
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