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Balanites aegyptiaca Carbohydrate Fractions and the Effect of Aqueous Extract of Mesocarp on Some Blood Parameters of CCl4 Induced Rats
Author: Salihu-Lasisi, M., *Akpabio C. J, Ogunsola M.O.
Publisher: International Journal of Toxicological and Pharmacological Research ISSN: 0975-5160
Published: 2014
Section: Faculty of Biomedical Sciences
Abstract
The mesocarp of fruits of Balanites aegyptiaca was analyzed for its biochemical constituents with estimation of different
fractions of carbohydrates present in the fruit mesocarp. The fruits mesocarp was then administered orally to rats to
assess blood parameters in CCl4 liver damaged rats. White albino rats (Rattus norvegicus) assigned to four (4) groups
containing fifteen (15) rats each were used to assess the effect of the aqueous extract of the mesocarp of the fruit
Balanites aegyptiaca on the CCl4 induced rats. Group 1 are the normal control (Nc) and group 2 are the diseased control
(Dc), while groups 3 and 4 are the test groups of animals administered orally with 0.08mg of raw (Tr) extract and 0.19mg
of concentrated (Tc) extracts per kg body weight respectively on daily basis. The result of the proximate composition
revealed that the fruit mesocarp has 36.42% carbohydrates with 50.89% of it as reducing sugar. Compared to the
controls, blood cells of the test rats revealed that there is significant increase (p<0.05) in the level of PCV, RBC,
haemoglobin, MCH, MCHC and neutrophils count of the Balanites aegyptiaca treated rats. This indicates that in a
diseased state, this fruits contains nutrients which can assist to restore and maintain biological functions of the body, if
regularly consumed.