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Prevalence of E. Coli Isolates from Urinary Tract Infected Patients Attending Selected Hospitals in Kisii County, Kenya
Author: Christine Gechemba Mokaya# , Eilu Emmanuel , Vidya Sankarapandian, Sarah Onkoba, Josephat Maniga , Emmanuel Ssali Dembe, Umar Uthman Shehu, Afolabi Abdullateef Opeyemi, Musyoka Angela Mumbua, Mutanule Fred, Hambali Kaltume Umar, Muhindo Mercy, John Tabakwot Ayuba, Sunil Kumar and Martin Odoki
Publisher: IDOSR JOURNAL OF BIOLOGY, CHEMISTRY AND PHARMACY
Published: 2023
Section: Faculty of Biomedical Sciences
Abstract
Urinary tract infections (UTIs) are a significant and growing global health concern, with E.
coli being the most common causing bacterium. The advent of antibiotic resistance has
worsened the difficulties associated with UTI therapy. This study looked at the prevalence
of multi-drug resistant E. coli isolates among UTI patients in Kisii County, Kenya. A total of
203 urine samples were collected, evaluated bacteriologically, and antibiotic sensitivity tests
were carried out. E. coli was detected in 20.87% of the samples. Notably, E. coli displayed
considerable antibiotic resistance, with amoxicillin exhibiting 100% resistance. In contrast,
E. coli isolates were imipenem susceptible. To avoid antibiotic abuse and treatment failures,
it is critical to screen for ESBL-producing isolates before administering antibiotics.