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Antioxidants and Pregnancy: Impact on Maternal and Fetal Health

Author: Emmanuel Ifeanyi Obeagu1, Getrude Uzoma Obeagu2, Joseph Obiezu Chukwujekwu Ezeonwumelu3, Esther Ugo Alum4,5 and Okechukwu Paul- Chima Ugwu5
Publisher: NEWPORT INTERNATIONAL JOURNAL OF BIOLOGICAL AND APPLIED SCIENCES
Published: 2023
Section: School of Allied Health Sciences

Abstract

Pregnancy represents a physiological state characterized by increased metabolic demands and heightened oxidative
stress, posing potential risks to both maternal health and fetal development. Oxidative stress, resulting from an
imbalance between reactive oxygen species (ROS) production and antioxidant defense mechanisms, has been
implicated in various pregnancy complications such as preeclampsia, gestational diabetes, preterm birth, and fetal
developmental abnormalities. Antioxidants, a diverse group of compounds abundant in fruits, vegetables, and certain
supplements, play a pivotal role in neutralizing ROS and mitigating oxidative damage. This comprehensive review
aims to elucidate the impact of antioxidants on maternal and fetal health during pregnancy. This paper underscores
the crucial influence of antioxidants on fetal development. Antioxidants have shown promise in protecting fetal cells
and tissues from oxidative damage, potentially reducing the risk of adverse pregnancy outcomes, birth defects, and
preterm birth. In conclusion, while antioxidants exhibit potential benefits in mitigating oxidative stress and improving pregnancy outcomes, further research is warranted to elucidate optimal dosages, potential interactions,
and long-term implications. This review offers insights into the current understanding of antioxidants in pregnancy
and emphasizes their significance in promoting maternal well-being and optimal fetal development.
Keywords: Antioxidants, Pregnancy, Maternal and Fetal Health