Abstract

Early Infant Diagnosis (EID) stands as a cornerstone in the global strategy to eradicate pediatric Human Immunodeficiency Virus (HIV) infections. This review delves into the pivotal role of EID in preventing the transmission of HIV from mothers to infants, emphasizing its significance in breaking the chain of transmission. The exploration encompasses key strategies such as Nucleic Acid Testing and Point-of-Care Testing, the integration of EID into broader Prevention of Mother-to-Child Transmission programs, and the persistent challenges hindering its full implementation. The review also sheds light on the latest technological advancements in EID, offering hope for improved efficiency and accessibility. As we navigate the complexities of accessibility barriers, loss to follow-up challenges, and turnaround time concerns, the review underscores the need for continued research, innovation, and global collaboration to ensure the successful implementation of EID and the realization of an HIV-free generation