Abstract

Gestational diabetes mellitus (GDM) introduces distinctive challenges to the maternal immune system, orchestrating a complex
interplay with the pivotal cellular dancers, neutrophils. This review delves into the dynamic world of neutrophil responses
during gestational diabetes, portraying a cellular ballet influenced by factors such as oxidative stress, cytokine modulation,
and their repercussions on both maternal and fetal health. The review amalgamates existing literature to provide a nuanced
understanding of the intricate dance of neutrophils in the context of gestational diabetes. The review delves into the unique
cellular dynamics at the maternal-fetal interface, shedding light on how neutrophils contribute to the immune homeostasis
crucial for a healthy pregnancy. The article concludes by discussing clinical implications and potential therapeutic strategies to
navigate the intricate cellular ballet, offering insights for future research and intervention in the realm of gestational diabetes
and immune modulation during pregnancy.