Abstract

Breast cancer is a complex and heterogeneous disease with various clinical outcomes, and its progression is influenced by a multitude of factors, including genetic components. This paper explores the molecular perspective of genetic influences on breast cancer progression, aiming to enhance our understanding of the underlying mechanisms driving the disease. The intricate interplay between inherited genetic mutations and sporadic genetic alterations within breast cancer cells significantly contributes to the initiation, development, and metastasis of the disease. We delve into the role of key genes involved in the regulation of cell cycle, DNA repair, and tumor suppression, shedding light on their impact on breast cancer pathogenesis. In conclusion, this review consolidates current knowledge on the genetic determinants of breast cancer progression from a molecular standpoint. The insights gained from unraveling the genetic intricacies of breast cancer pave the way for innovative diagnostic and therapeutic approaches, ultimately contributing to improved patient outcomes and a more comprehensive understanding of this formidable disease