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The Impact of HIV Infection on Eosinophil Levels during Pregnancy: A Narrative Review

Author: Emmanuel Ifeanyi Obeagu1* and Getrude Uzoma Obeagu2
Publisher: Haematology International Journal
Published: 2024
Section: School of Allied Health Sciences

Abstract

Human Immunodeficiency Virus (HIV) infection poses unique challenges during pregnancy, affecting maternal health and
potentially impacting the developing fetus. This systematic review explores the intricate relationship between HIV and
eosinophils, a critical component of the immune system, during pregnancy. As HIV induces immunosuppression, understanding
its specific effects on eosinophil levels is crucial for predicting maternal health outcomes and vertical transmission risks. The
review also delves into the potential influence of antiretroviral therapy on modulating eosinophil function. By synthesizing
existing literature, this review aims to provide a comprehensive understanding of the complex interplay between HIV infection,
eosinophils, and pregnancy, offering insights for future research directions and potential therapeutic interventions.
Keywords: HIV Infection; Eosinophils; Pregnancy; Immunosuppression; Maternal Health; Vertical Trans