Abstract

The coexistence of diabetes mellitus (DM) and sickle cell anemia (SCA) presents a complex medical challenge, necessitating an
integrated approach to patient care. This review explores the interplay between diabetes and sickle cell anemia, addressing
the epidemiology, pathophysiological intricacies, and the compounded complications associated with these comorbidities.
Emphasizing the need for an interdisciplinary care model, the review discusses the challenges in patient care, encompassing
both physiological and psychosocial dimensions. Furthermore, it outlines innovative treatment strategies, including medication
management and lifestyle interventions, aiming to optimize outcomes for individuals navigating the dual management of
diabetes and sickle cell anemia. By synthesizing current research findings and highlighting areas for future investigation, this
review provides valuable insights into the complexities of dual management and offers a foundation for enhancing the quality
of care for this unique patient population.