Abstract

Pregnancy in women with Human Immunodeficiency Virus (HIV) presents a unique set of challenges, necessitating a closer
examination of the immune system’s responses, particularly in relation to eosinophil dynamics. This comprehensive review
explores the fluctuations in eosinophil counts during pregnancy in HIV-positive women, emphasizing the intricate interplay
between the immune system, maternal health, and the risk of vertical transmission. The impact of Antiretroviral Therapy (ART)
on eosinophil regulation is also investigated, offering valuable insights into potential therapeutic strategies. By unraveling the
complexities of eosinophil dynamics in this specific population, this review aims to contribute to a deeper understanding of
maternal immune adaptations and pave the way for targeted interventions to optimize health outcomes for both mothers and
infants.