Abstract

Gestational diabetes mellitus (GDM) represents a complex metabolic disorder during pregnancy, impacting both
maternal and fetal health. Recent investigations have shed light on the intricate interplay between gestational diabetes
and neutrophil activation, revealing a cellular symphony that contributes to the pathophysiology of this condition.
This review explores the current state of knowledge regarding the relationship between gestational diabetes and
neutrophil activation, focusing on the molecular mechanisms, immune responses, and inflammatory cascades that
orchestrate this cellular symphony. Understanding these interactions is crucial for unraveling the complexities of
gestational diabetes and may pave the way for novel therapeutic interventions aimed at mitigating the associated
inflammatory burden and improving pregnancy outcomes.