Abstract

This review delves into the intricate relationship between sickle cell anemia and diabetes, shedding light on the unique challenges and considerations in diabetes care for individuals affected by this hemoglobinopathy. Sickle cell anemia, a hereditary blood disorder characterized by abnormal hemoglobin, introduces complexities in managing diabetes that extend beyond those encountered in the general population. Chronic inflammation, oxidative stress, and an increased risk of vaso-occlusive crises associated with sickle cell anemia can impact insulin resistance and glycemic control. Through an examination of existing literature, this review synthesizes available knowledge, addresses research gaps, and proposes tailored care strategies. Emphasizing the need for a comprehensive and personalized approach to diabetes care in this unique patient demographic, the review aims to contribute to the advancement of evidence-based practices and improve clinical management for individuals navigating the complex intersection of sickle cell anemia and diabetes.