Abstract

Natural products have garnered attention as potential sources of novel antimicrobial agents amidst the global
challenge of antimicrobial resistance. Mondia whitei, a plant indigenous to Africa, holds promise due to its diverse
array of phytochemical constituents. This study investigated the antifungal properties of the aqueous extract of
Mondia whitei root bark against Candida albicans and Sacromyces spp. Phytochemical screening revealed the
presence of alkaloids, tannins, volatile oils, and flavonoids. Susceptibility testing demonstrated dose-dependent
inhibition of both fungal strains by the extract. These findings underscore the therapeutic potential of Mondia
whitei as a natural antifungal agent deserving further exploration.
Keywords: Antifungal, Mondia whitei, Candida albicans, Sacromyces spp