Abstract

CD8 T cells are key players in the immune response against HIV, tasked with identifying and eliminating virus-infected cells. However, the battle between HIV and CD8 T cells is complex, marked by a dynamic interplay between viral evasion strategies and host immune responses. This review delves into the intricate relationship between CD8 T cells and HIV, exploring the mechanisms of viral control, immune evasion tactics employed by HIV, and the implications for therapeutic interventions, including antiretroviral therapy (ART). By dissecting the dynamics of CD8 T cell responses in HIV infection, we glean insights into the immune battlefield, shedding light on potential strategies for bolstering immune-mediated control of the virus and advancing towards a functional cure