Abstract

This study shows the testicular assessment of Abelmoschus esculentus
treated animals. Twenty-one animals weighing between
100g-120g were grouped into three groups, seven animals for each
group. The rats in group A served as the control and fed with normal
rat chew and water while the animals in group B treated with 1.0mg/
KgBw and C 3.0 mg/KgBw aqueous extract of Abelmoschus esculentus
orally for 14 days. All the animals were sacrificed a day after
the administration and the testes removed for histological tissues
processing using Hematoxylin and Eosin (H&E) stain. The caudal
part of the epididymis was harvested for collection of semen for analysis.
Result of the study shows a significant (p<0.05) increase in
final body weight of all the animals compared with their initial body
weight while result from semen analysis shows a significant increase
(p<0.05) in percentage sperm motility in the control and high dose
group, the highest percentage of sperm morphology was observed
in the control group while the sperm vitality reveals a significant decrease
(p<0.05) in the low dose and high dose. Results of the histology
of the control group showed a normal histology of the seminiferous
tubules (round cells), low dose showed seminiferous tubules
with acute loss of Germinal cell area (G) and high dose showed testicular regression (loss of interstitial space, IT), tubular architecture
and Germ layer (G).