Abstract

The granule was evaluated and had fair flow properties using tests such as bulk density. Ibuprofen tablets of 400mg
were then formulated from granules by compression. The process of tableting was carried out at Mbarara University
of science and technology using the Pharmbiotrac laboratories. The tablet properties such as friability test,
disintegration test, hardness test was carried out and the results were fairly good. Unfortunately, only one Batch
was able to pass the dissolution test and all batches were not able to yield about 95% drug concentration on drug
assay. The study's primary goal was to formulate tablets of ibuprofen where Musa acuminata starch is used as a
binder using wet granulation method. The Musa acuminata starch was used to form a mucilage which was used as a
binder in the formulation. Musa acuminata starch showed good binding properties, this is seen in the hardness test.
The formulated tablets had a good crushing strength. The disintegration of the tablets was fair. But the batches
were not able to pass the drug assay test, the tablets contained 80% of the active ingredient.Musa acuminata starch
has good physical properties and is a good binder and could be a competitor of corn starch as a binder however
compatibility tests are required to prove its compatibility with active ingredient ibuprofen