Abstract

Benign Prostatic Hyperplasia (BPH) is a noncancerous increase in size of the prostate gland. The symptoms of BPH
are mostly lower urinary tract symptoms and these include waking up to urinate at night, urgency, frequency,
incontinence of urine and inability to empty the bladder completely and weak urine stream. Nocturia in particular
has been found to have negative effect on quality of sleep, energy or vitality. Men realizes they have prostate
enlargement when they start experiencing lower urinary tract symptoms. Several new biomarkers for individuals
with raised PSA concentrations or those diagnosed with prostate cancer are likely to identify individuals who can
be spared aggressive treatment.