Abstract

Neonatal sepsis (NS) is a leading cause of neonatal morbidity and mortality and is considered
a global public health challenge. The organisms and pathogens most commonly associated
with neonatal sepsis vary by country. Pathogens range from Gram-positive and Gramnegative
bacteria to viruses and fungi, with bacteria being the most commonly identified.
Bacteria most commonly involved include Staphylococcus aureus, coagulase-negative
staphylococci (CONS), Streptococcus pneumoniae, Streptococcus pyogenes, Escherichia coli,
Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhi, and Group B
Streptococcus increase, or urine culture is usually delayed for a day or two. A battery of tests,
including C-reactive protein, total leukocyte count, absolute neutrophil count, platelet count,
neutrophil cytoplasmic vacuolization, and polymorphic gastric aspiration cytology, was
performed in neonates with a clinical diagnosis of NS. It's an excellent screening tes