KIU Publications

Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.

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2024 School of Allied Health Sciences

Evaluation of Thyroid Hormones in Congestive Heart Failure Subjects Attending Federal University Teaching Hospital Owerri, Imo State

Ukamaka Edward1, Esther E. Iwuajoku1 and *Emmanuel Ifeanyi Obeagu2

2024 | Elite Journal of Laboratory Medicine | Pp. 1-7

This study was carried out to evaluate levels of thyroid hormones in patients with congestive heart failure. A total of sixty (60) subjects aged forty-five (45) – sixty-five (65) years were recruited for the study and were divided into two groups subjects wit...

2024 School of Allied Health Sciences

Erythropoietin Receptor Signaling in HIV: Implications for Therapy

*Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu3

2024 | Elite Journal of Haematology | Pp. 46-62

Human Immunodeficiency Virus (HIV) remains a global health challenge, necessitating continuous exploration of novel therapeutic avenues. Erythropoietin (EPO), traditionally recognized for its role in erythropoiesis, has emerged as a multifaceted cytokine with...

2024 School of Allied Health Sciences

Eosinophilic Modulation of Neonatal Vaccine Immune Responses in HIV-Exposed Infants

Emmanuel Ifeanyi Obeagu1* and Getrude Uzoma Obeagu2

2024 | Haematology International Journal | Pp. 1-6

The intricate interplay between eosinophils and neonatal vaccine immune responses in HIV-exposed infants has emerged as acaptivating avenue of research, offering insights into the multifaceted dynamics of early-life immunity. This review synthesizescurrent kn...

2024 School of Allied Health Sciences

Eosinophil Count Fluctuations during Pregnancy in Women with HIV: A Comprehensive Review

Emmanuel Ifeanyi Obeagu1* and Getrude Uzoma Obeagu2

2024 | Haematology International Journal | Pp. 1-9

Pregnancy in women with Human Immunodeficiency Virus (HIV) presents a unique set of challenges, necessitating a closerexamination of the immune system’s responses, particularly in relation to eosinophil dynamics. This comprehensive reviewexplores the fluctuat...

2024 School of Allied Health Sciences

Effect of metformin on vitamin B12 and homocysteine levels among Sudanese with type 2 diabetes mellitus

Sumaia Mohammed Ali AL-Ghaili1, Eltayeb Mohammed Ahmed Tayrab2,3 and Emmanuel Ifeanyi Obeagu4

2024 | Elite Journal of Medicine | Pp. 85-103

Metformin is the first-line treatment for type 2 diabetes mellitus (T2DM), and hyperglycemia. When taken in high doses or for an extended period, metformin may decrease vitamin B12 (VitB12) level and may increase homocysteine (Hcy) level. There has been no re...

2024 School of Allied Health Sciences

Dual Management: Diabetes and Sickle Cell Anemia in Patient Care

Emmanuel Ifeanyi Obeagu1* and Getrude Uzoma Obeagu2

2024 | Haematology International Journal | Pp. 1-7

The coexistence of diabetes mellitus (DM) and sickle cell anemia (SCA) presents a complex medical challenge, necessitating anintegrated approach to patient care. This review explores the interplay between diabetes and sickle cell anemia, addressingthe epidemi...

2024 School of Allied Health Sciences

Drug-Drug Interactions in the Management of Coexisting Sickle Cell Anemia and Diabetes

*Emmanuel Ifeanyi Obeagu1, Ebere Emilia Ayogu2,3, Chinyere Nkemjika Anyanwu4 and Getrude Uzoma Obeagu

2024 | Elite Journal of Medical Sciences | Pp. 1-9

This review scrutinizes the intricate landscape of drug-drug interactions in the management of coexisting sickle cell anemia and diabetes, two chronic conditions that often intersect, challenging healthcare providers in their pursuit of optimal patient care....

2024 School of Allied Health Sciences

Dendritic Cell Function in HIV-Infected Pediatric Populations

*Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

2024 | Elite Journal of Immunology | Pp. 1-14

Pediatric HIV infection presents unique challenges due to the dynamic interplay between the virus and the developing immune system. Dendritic cells, key regulators of immune responses, play a crucial role in shaping the outcomes of HIV infection in children....

2024 School of Allied Health Sciences

Cytokine Modulation as a Strategy for Type 1 Diabetes Intervention: Unraveling Immunological Complexities for Therapeutic Advancements

Emmanuel Ifeanyi Obeagu1 and Getrude Uzoma Obeagu2

2024 | Elite Journal of Immunology | Pp. 65-75

Type 1 diabetes (T1D) stands as a formidable autoimmune challenge, marked by the progressive destruction of insulin-producing pancreatic beta cells. This review explores the potential of cytokine modulation as a strategic intervention in T1D, acknowledging th...

2024 School of Allied Health Sciences

Current Trends and Challenges in Blood Transfusion for Individuals with HIV

*Emmanuel Ifeanyi Obeagu1, Chioma Ibe2, Getrude Uzoma Obeagu3 and Chinyere Nkemjika Anyanwu4

2024 | International Journal of Innovative and Applied Research | Pp. 47-63

This review article provides an in-depth exploration of the current trends and challenges associated with blood transfusion practices in individuals living with HIV. As advancements in antiretroviral therapy (ART) have significantly improved the life expectan...