Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.
Scholarly Work
Search peer-reviewed articles, reports, books, policy briefs and other scholarly outputs by KIU researchers and collaborators.
2026 | RESEARCH INVENTION JOURNAL OF BIOLOGICAL AND APPLIED SCIENCES | Pp. 77-86
Metabolomics, the comprehensive analysis of small-molecule metabolites in biological samples, offers significant potential to improve health outcomes and support sustainable development in low- and middle-income countries (LMICs). However, its implementation...
2026 | RESEARCH INVENTION JOURNAL OF BIOLOGICAL AND APPLIED SCIENCES | Pp. 53-62
Whole-genome sequencing (WGS) has emerged as a powerful genomic tool for diagnosing rare Mendelian disorders, offering substantial gains in clinical validity and clinical utility compared with traditional single-gene or panel-based approaches. By simultaneous...
2026 | RESEARCH INVENTION JOURNAL OF BIOLOGICAL AND APPLIED SCIENCES | Pp. 68-76
Type 2 diabetes (T2D) represents a growing global health challenge, with early detection of at-risk individuals being critical for prevention and management. Traditional risk factors and biomarkers, while informative, have limited predictive accuracy, particu...
2026 | RESEARCH INVENTION JOURNAL OF BIOLOGICAL AND APPLIED SCIENCES | Pp. 13-20
Sickle cell disease (SCD) is a prevalent monogenic disorder with significant morbidity and mortality worldwide, particularly in low- and middle-income countries. Early diagnosis through population screening is critical to reduce adverse health outcomes and en...
2026 | RESEARCH INVENTION JOURNAL OF BIOLOGICAL AND APPLIED SCIENCES | Pp. 1-7
CRISPR-based diagnostics represent a promising innovation in the detection of human immunodeficiency virus (HIV), with potential to improve early diagnosis, expand population screening, and strengthen public health responses. This paper examines the clinical...
2026 | IAA Journal of Applied Sciences | Pp. 44-48
Therapeutic antioxidants have emerged as promising modulators of immune function by mitigating oxidative stress and influencing inflammatory pathways. Reactive oxygen species (ROS), when produced in excess, can damage cellular components including DNA, lipids...
2026 | IAA Journal of Applied Sciences | Pp. 30-35
Diabetes mellitus arises through a multifaceted network of metabolic derangements, prominently featuring insulin resistance, chronic inflammation, and oxidative stress. These three processes do not occur in isolation; rather, they form a self-reinforcing tria...
2026 | IAA Journal of Applied Sciences | Pp. 6-11
Rheumatoid factor (RF), a classic autoantibody directed against the Fc portion of immunoglobulin G (IgG), has long been recognized as a hallmark of rheumatoid arthritis (RA). However, emerging evidence indicates that RF positivity extends far beyond rheumatol...
2026 | IAA Journal of Biological Sciences | Pp. 133-141
Population genomics is reshaping breast cancer prevention by enabling the identification of individuals and families at elevated genetic risk before disease onset. Advances in genomic technologies have made populationscale screening for high-penetrance breast...
2026 | IAA Journal of Biological Sciences | Pp. 125-132
Polygenic risk scores (PRS) have emerged as promising tools for stratifying breast cancer risk and informing screening and prevention strategies. However, their clinical utility in African ancestry populations remains limited due to poor transferability, misc...