KIU Publications

Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.

Scholarly Work

KIU publications archive

Search peer-reviewed articles, reports, books, policy briefs and other scholarly outputs by KIU researchers and collaborators.

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2026 School of Natural and Applied Sciences

Diabetes Complications in Low-Income Countries: A Narrative Review

Wambui Kibibi J.

2026 | IDOSR JOURNAL OF APPLIED SCIENCES | Pp. 89-97

Diabetes has emerged as a major public health challenge in low-income and low- and middle-income countries (LMICs), where its complications contribute disproportionately to morbidity, mortality, and economic burden. This narrative review examines the epidemio...

2026 School of Natural and Applied Sciences

Diabetes and Obesity: Mechanistic Insights

Wambui Kibibi J.

2026 | IDOSR JOURNAL OF APPLIED SCIENCES | Pp. 83-88

Obesity and type 2 diabetes (T2D) are interrelated global health challenges with rising prevalence and profound socioeconomic impact. Central adiposity is a key driver of metabolic dysfunction, contributing to insulin resistance, β-cell stress, and dysregulat...

2026 School of Natural and Applied Sciences

Diabetes and Mental Health: A Scholarly Review

Mugo Moses H.

2026 | IDOSR JOURNAL OF APPLIED SCIENCES | Pp. 18-25

Diabetes and mental health disorders are two of the most prevalent chronic conditions globally, each exerting a substantial burden on individuals, health systems, and societies. Increasing evidence demonstrates a complex, bidirectional relationship between di...

2026 School of Natural and Applied Sciences

Diabetes and Kidney Disease: Interconnections, Mechanisms, and Implications for Care

Mugo Moses H.

2026 | IDOSR JOURNAL OF APPLIED SCIENCES | Pp. 6-17

Diabetes mellitus and chronic kidney disease are closely interconnected global health challenges with profound clinical, economic, and societal implications. Diabetes is one of the leading causes of chronic kidney disease worldwide, and diabetic kidney diseas...

2026 School of Natural and Applied Sciences

Chronic Pain Management in War Survivors

Mugo Moses H.

2026 | IDOSR JOURNAL OF APPLIED SCIENCES | Pp. 1-5

Chronic pain is a prevalent and disabling consequence of war-related injuries, significantly impacting the physical, psychological, and social well-being of survivors. War injuries ranging from blast and shrapnel wounds to burns and crush injuries trigger com...

2026 School of Natural and Applied Sciences

Toxicological Perspectives on Herbal and Nutraceutical Antioxidants in Diabetes Management: Benefits, Risks, and Hepatotoxicity Profiles

Nambi Namusisi H.

2026 | IDOSR JOURNAL OF SCIENCE AND TECHNOLOGY | Pp. 72-77

Herbal and nutraceutical antioxidants are widely used as complementary therapies in type 2 diabetes mellitus (T2DM) to mitigate oxidative stress, improve glycaemic control, and prevent complications. Numerous plant- derived compounds-including polyphenols, fl...

2026 School of Natural and Applied Sciences

The Antioxidant Axis in Protecting Metabolic and Reproductive Health: Bridging Hepatoprotection, Neuroprotection, and Fertility Restoration

Wambui Kibibi J.

2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 52-56

persistent oxidative stress, linking hepatic, neurological, and reproductive dysfunction. Oxidative stress arises from an imbalance between reactive oxygen and nitrogen species (ROS/RNS) and endogenous antioxidant defenses, leading to lipid peroxidation, prot...

2026 Faculty of Science and Technology

Targeting Oxidative Stress to Restore Immune Balance: Phytochemical Interventions in Cancer and Chronic Inflammation

Kato Jumba K.

2026 | IDOSR JOURNAL OF SCIENCE AND TECHNOLOGY | Pp. 67-71

Oxidative stress is both a driver and a consequence of dysregulated immunity across cancer and chronic inflammatory diseases. Reactive oxygen and nitrogen species (ROS/RNS) shape antigen presentation, cytokine networks, and cell death pathways; at pathologica...

2026 Faculty of Science and Technology

Stress-Mediated Hepatotoxicity and the Protective Role of Phytomedicines

Mugisha Emmanuel K.

2026 | IDOSR JOURNAL OF SCIENCE AND TECHNOLOGY | Pp. 46-50

Stress-mediated hepatotoxicity-liver injury driven or amplified by oxidative stress, endoplasmic reticulum (ER) stress, mitochondrial dysfunction, and inflammation-represents a convergent pathway for a broad range of chemical, biological and metabolic insults...

2026 Faculty of Biomedical Sciences

Rheumatoid Factor as a Metabolic Biomarker: Emerging Links Between Autoantibody Biology, Insulin Resistance, and Type 2 Diabetes

Odile Patrick Thalia

2026 | IDOSR JOURNAL OF SCIENCE AND TECHNOLOGY | Pp. 1-6

Rheumatoid factor (RF), traditionally regarded as a serological marker of rheumatoid arthritis (RA), is increasingly recognized for its broader relevance in systemic inflammatory states. Accumulating evidence suggests that RF positivity may reflect underlying...