Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.
Scholarly Work
Search peer-reviewed articles, reports, books, policy briefs and other scholarly outputs by KIU researchers and collaborators.
2026 | IDOSR JOURNAL OF BIOLOGY, CHEMISTRY AND PHARMACY | Pp. 1-7
Artemisinin and its derivatives, traditionally employed as antimalarial agents, had demonstrated pleiotropic biological activities including anti-inflammatory, antioxidant, and metabolic regulatory properties. Recent preclinical investigations suggested poten...
2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 116-122
Artemisinin resistance in Plasmodium falciparum posed a critical threat to global malaria control, with delayed parasite clearance and treatment failures increasingly reported across endemic regions. This review evaluated the biochemical rationale and clinica...
2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 107-115
Artemisinin-based combination therapies represented the cornerstone of contemporary malaria treatment, yet emerging resistance in Plasmodium falciparum threatens global malaria control achievements. Artemisinin resistance manifested as delayed parasite cleara...
2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 27-33
Anaemia and oxidative stress are frequently comorbid in metabolic disorders such as type 2 diabetes mellitus, obesity, metabolic syndrome, and chronic kidney disease. The two processes are bi-directionally linked: oxidative stress perturbs iron handling, eryt...
2026 | IDOSR JOURNAL OF SCIENCE AND TECHNOLOGY | Pp. 7-12
Human Immunodeficiency Virus (HIV) infection is characterized by persistent immune activation, chronic inflammation, and oxidative stress, which collectively accelerate CD4+ T-cell depletion and contribute to progressive immune dysfunction. Oxidative stress,...
2026 | IDOSR JOURNAL OF SCIENCE AND TECHNOLOGY | Pp. 83-87
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia, which contributes to systemic complications including cardiovascular, renal, and reproductive dysfunction. Reproductive impairments in both males and females are...
2026 | IDOSR JOURNAL OF SCIENCE AND TECHNOLOGY | Pp. 34-39
Diabetes mellitus, particularly type 2 diabetes mellitus (T2DM), is increasingly recognized as a state of chronic immunometabolic dysfunction driven in large part by oxidative stress and impaired antioxidant responses. Hyperglycaemia, dyslipidaemia, and adipo...
2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 102-106
Antimicrobial resistance (AMR) in the treatment of diarrheal diseases represents a significant and escalating public health challenge in sub-Saharan Africa. The region is particularly vulnerable due to factors such as poor sanitation, inadequate diagnostic in...
2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 89-94
Malaria remained a leading cause of morbidity and mortality in Sub-Saharan Africa, where Plasmodium falciparum demonstrates increasing resistance to multiple antimalarial agents. The molecular basis of this resistance involved complex genetic mutations affect...
2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 95-101
Plasmodium falciparum remained the deadliest malaria parasite, causing over 600,000 deaths annually, with antimalarial drug resistance threatening global control efforts. Multiple resistance mechanisms have emerged against quinolines, antifolates, and artemis...