KIU Publications

Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.

Scholarly Work

KIU publications archive

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2026 Faculty of Biomedical Sciences

Exploring Novel Phytochemicals as Strategies in the Fight Against Antimicrobial Resistance

Esther Ugo Alum, Basil Uchechukwu Nwali, Ada Ak. Akwari, Akunna Perpetua Emeruwa, David Chukwu Obasi, Prince Nkemakolam Okoroh, and Ugonna Cassandra Aniokete.

2026 | sage | Pp. 1-12

Antimicrobial resistance (AMR) is accelerating worldwide and is eroding the effectiveness of frontline antibiotics, driving treatmentfailure, prolonged illness, higher costs, and avoidable mortality. Medicinal plants have proven to be a potential source of na...

2026 Faculty of Biomedical Sciences

Chelesta-8,24-dien-3-ol in Ficus exasperata leaves enhances the prevention of sodium nitrite induced hypoxia by binding to HIF 1 and NF-κB

Dorcas Ibukun Akinloye , Ceaser Antiya Moses, Esther Ugo Alum, Theophilus Aghogho Jarikre, Toluwalase Ayobami Adeosun, Abdulazeez Timileyin Kolawole, Iyanu Solomon Awonaiya, Esther Oluwabusayomi Odeniyi & Oluseyi Adeboye Akinloye

2026 | Scientific Reports | Pp. 4822

In-silico and in-vivo methods were used to study Ficus exasperata leaves’ n-hexane ethyl acetate fraction (NHEAF) phytochemicals that may protect against NaNO2-induced hypoxic stress. The impact of NHEAF on enzymatic and non-enzymatic antioxidants, total ATPa...

2026 School of Pharmacy

Zinc Finger Nuclease-Mediated CCR5 Disruption as Host-Directed Therapy Against HIV Infection

Bwanbale Geoffrey David

2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 1-5

Human immunodeficiency virus infection remains a major global health challenge despite major advances in antiretroviral therapy. Current treatment requires lifelong drug administration and does not eliminate latent viral reservoirs, creating a persistent need...

2026 School of Pharmacy

Typhoid Fever among Children Under 15 Years in Africa: Epidemiology, Clinical Burden, Diagnosis, Treatment and Prevention

Masika Anna Mahinda

2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 53-57

Typhoid fever remains a preventable cause of illness and death among African children, especially where safe water, sanitation, and hygiene are limited. Caused by Salmonella Typhi, it spreads mainly through food or water contaminated with human faeces. Diseas...

2026 School of Pharmacy

The Role of Smoking and Alcohol in Arthritis Progression in East Africa

Muhindo Anitah

2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 6-10

Arthritis represents a growing non-communicable disease (NCD) burden in East Africa, driven by demographic transition, urbanization, lifestyle changes, and persistent inflammatory triggers. Tobacco smoking and alcohol consumption are modifiable behavioral exp...

2026 School of Pharmacy

The Role of Nutrition and Diet in Managing Diabetes in African Rural Areas: A Narrative Review of Clinical Evidence, Rural Food Systems and Feasible Interventions Masika Anna Mahinda

Masika Anna Mahinda

2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 58-62

Diabetes is increasing rapidly across Africa, yet access to diagnosis, treatment, and nutrition support remains unequal, especially in rural communities. Nutrition is essential because it affects blood glucose, weight, blood pressure, cholesterol, medication...

2026 School of Pharmacy

The Prostate-Liver-Immune Axis: Shared Pathways in BPH, Hepatotoxicity, and Systemic Inflammation

Mpora Kakwanzi Evelyn

2026 | IDOSR JOURNAL OF APPLIED SCIENCES | Pp. 35-41

Emerging evidence indicates that the prostate, liver, and immune system are linked through common molecular and cellular pathways that influence disease development beyond organ-specific boundaries. Traditionally, benign prostatic hyperplasia (BPH) has been v...

2026 School of Natural and Applied Sciences

The Bidirectional Relationship Between Diabetes and Tuberculosis in Nigeria: Epidemiological Insights and Control Strategies

Kibibi Wairimu H.

2026 | ionship Between Diabetes and Tuberculosis in Nigeria: Epidemiological Insights and Control Strategies. IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 94-98

Nigeria faces a double burden of tuberculosis (TB) and diabetes mellitus (DM), creating a syndemic in which DM increases the risk of active TB and worsens TB outcomes, while TB and its treatment can destabilize glycaemic control and unmask previously undiagno...

2026 School of Pharmacy

Sub-Saharan Africa Pregnant Women: Intermittent Preventive Therapy and Malaria-Related Birth Outcomes

Winniefred Nankya

2026 | IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS | Pp. 90-93

Malaria in pregnancy remains a major public health concern in sub-Saharan Africa, where transmission intensity is high and pregnant women are particularly vulnerable to infection. Physiological and immunological changes during pregnancy increase susceptibilit...

2026 School of Pharmacy

Social Inequality and Pandemic Mortality Patterns: Structural Determinants, Mechanisms, and Policy Implications

Arionget Jemima

2026 | IDOSR JOURNAL OF APPLIED SCIENCES | Pp. 77-82

Pandemics have repeatedly revealed and amplified pre-existing social inequalities, producing disproportionate mortality among marginalized populations. Differences in income, race and ethnicity, education, occupation, housing conditions, and access to healthc...