Research outputs, reports, policy briefs and knowledge products from KIU scholars and partners.
Scholarly Work
Search peer-reviewed articles, reports, books, policy briefs and other scholarly outputs by KIU researchers and collaborators.
2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 115-119
Type 2 diabetes mellitus was characterized by chronic hyperglycemia resulting from insulin resistance and impaired regulation of hepatic glucose production. Excessive hepatic gluconeogenesis was a major contributor to fasting hyperglycemia and remained incomp...
2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 110-114
Obesity and type 2 diabetes (T2D) represent a major global health burden, with increasing prevalence linked to sedentary lifestyles, poor dietary habits, and genetic predisposition. These conditions are strongly interconnected through a range of metabolic dys...
2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 105-109
Sickle cell disease (SCD), particularly sickle cell anemia (HbSS), is intrinsically a chronic hemolytic anemia, but the severity and hospital burden of anemia vary widely across patients and care settings. In Uganda, where SCD is common and malaria and undern...
2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 100-104
Cardiovascular and renal complications remained the leading causes of morbidity and mortality in type 2 diabetes, affecting approximately 537 million adults globally in 2021 with projections exceeding 783 million by 2045. Sodium-glucose cotransporter-2 (SGLT2...
2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 94-99
Obesity and type 2 diabetes (T2D) are major contributors to the global burden of chronic diseases, with their coexistence exacerbating the health challenges faced by millions of people worldwide. The close association between obesity and insulin resistance in...
2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 89-93
Malaria remained a major global health challenge, with uncomplicated malaria accounting for most clinical cases in endemic regions. Artemisinin-based combination therapy remained the cornerstone of treatment, and lumefantrine played a crucial role as the long...
2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 83-88
Plant-derived bioactives offer pleiotropic actions relevant to obesity and cardiometabolic risk, including modulation of appetite and gut hormone signaling, suppression of adipose inflammation, improvement of insulin sensitivity, regulation of lipid metabolis...
2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 77-82
Diabetes and metabolic syndrome (MetS) are interconnected metabolic disorders characterized by hyperglycemia, insulin resistance, central obesity, dyslipidemia, hypertension, oxidative stress, and chronic inflammation. Plant-derived bioactives including polyp...
2026 | IDOSR JOURNAL OF EXPERIMENTAL SCIENCES | Pp. 67-76
Phytochemicals with anti-obesity potential modulate adipogenesis, lipolysis, and thermogenesis through pleiotropic effects on transcriptional networks, mitochondrial function, and inflammatory signaling. However, their clinical impact is frequently limited by...
2026 | IDOSR JOURNAL OF SCIENTIFIC RESEARCH | Pp. 119-130
Insulin resistance and progressive pancreatic β-cell failure are the twin biological engines of type 2 diabetes and major determinants of long-term complications. Phytochemicals such as curcumin, resveratrol, quercetin, epigallocatechin gallate, berberine, gi...